Application.CFC Reference
You implement methods in Application.cfc to handle ColdFusion application events and set variables in the CFC to configure application characteristics.
Note: Although Windows is case-insensitive, you should always start the Application.cfc filename with an uppercase A. Both application.cfc and Application.cfc are reserved words.
Note: If your application has an Application.cfc, and an Application.cfm or onRequestend.cfm page, ColdFusion ignores the CFM pages